NHC-Cu-Catalyzed Protoboration of Monosubstituted Allenes. Ligand-Controlled Site Selectivity, Application to Synthesis and Mechanism

作者：Meng Fanke; Jung Byunghyuck; Haeffner Fredrik; Hoveyda Amir H^*

来源：Organic Letters, 2013, 15(6): 1414-1417.

DOI：10.1021/ol4004178

Two types of NHC-Cu complexes catalyze protoborations of terminal allenes to afford valuable 1,1- or trisubstituted vinylboron species with high site selectivity and stereoselectivity. The scope of the method, application to natural product synthesis, and mechanistic basis for the observed selectivity trends are presented.

• 出版日期2013-3-15