Atherogenic Risk Factors and Hearing Thresholds

作者：Frederiksen Thomas Winther^*; Ramlau Hansen Cecilia Host; Stokholm Zara Ann; Grynderup Matias Brodsgaard; Hansen Ase Marie; Lund Soren Peter; Vestergaard Jesper Medom; Kristiansen Jesper; Bonde Jens Peter; Kolstad Henrik Albert

来源：Audiology and Neuro-Otology, 2014, 19(5): 310-318.

DOI：10.1159/000365439

• Sensorineural hearing loss
• Blood lipids
• Glycosylated hemoglobin
• Smoking habits
• Body mass index
• Ambulatory blood pressure

The objective of this study was to evaluate the influence of atherogenic risk factors on hearing thresholds. In a cross-sectional study we analyzed data from a Danish survey in 20092010 on physical and psychological working conditions. The study included 576 white-and blue-collar workers from children's day care units, financial services and 10 manufacturing trades. Associations between atherogenic risk factors (blood lipids, glycosylated hemoglobin, smoking habits, body mass index (BMI), and ambulatory blood pressure) and hearing thresholds were analyzed using multiple linear regression models. Adjusted results suggested associations between smoking, high BMI and triglyceride level and low high-density lipoprotein level and increased low-frequency hearing thresholds (average of pure-tone hearing thresholds at 0.25, 0.5 and 1 kHz). Furthermore, an increasing load of atherogenic risk factors seemed associated with increased low-frequency hearing thresholds, but only at a borderline level of statistical significance. Associations were generally strongest with hearing levels of the worst hearing ear. We found no statistically significant associations between atherogenic risk factors and high-frequency hearing thresholds (average of pure-tone hearing thresholds at 4, 6 and 8 kHz).

• 出版日期2014