Nanotechnology-Driven Therapeutic Interventions in Wound Healing: Potential Uses and Applications

作者：Hamdan, Suzana; Pastar, Irena; Drakulich, Stefan; Dikici, Emre; Tomic-Canic, Marjana; Deo, Sapna; Daunert, Sylvia^*

来源：ACS Central Science, 2017, 3(3): 163-175.

DOI：10.1021/acscentsci.6b00371

• DIABETIC FOOT ULCERS
• ENDOTHELIAL GROWTH-FACTOR
• STEM-CELL NICHE
• NITRIC-OXIDE NANOPARTICLES
• OF-THE-ART
• IN-VITRO
• DRUG-DELIVERY
• VENOUS ULCERS
• SKIN WOUNDS
• NONHEALING WOUNDS

The chronic nature and associated complications of nonhealing wounds have led to the emergence of nanotechnology-based therapies that aim at facilitating the healing process and ultimately repairing the injured tissue. A number of engineered nanotechnologies have been proposed demonstrating unique properties and multiple functions that address specific problems associated with wound repair mechanisms. In this outlook, we highlight the most recently developed nanotechnology-based therapeutic agents and assess the viability and efficacy of each treatment, with emphasis on chronic cutaneous wounds. Herein we explore the unmet needs and future directions of current technologies, while discussing promising strategies that can advance the wound-healing field.

• 出版日期2017-3-22