Use of Intrapulmonary Percussive Ventilation (IPV) in the Management of Pulmonary Complications of an Infant With Osteogenesis Imperfecta

作者：Nino Gustavo; McNally Paul; Miske Laura J; Hickey Eileen; Panitch Howard B^*

来源：Pediatric Pulmonology, 2009, 44(11): 1151-1154.

DOI：10.1002/ppul.21112

• osteogenesis imperfecta
• intrapulmonary percussive ventilation
• airway clearance
• atelectasis
• tracheomalacia
• bronchomalacia

Osteogenesis imperfecta (01) is a genetic disorder characterized by abnormal collagen formation and short stature. These patients present with frequent vertebral, rib, and long bone fractures. There are many respiratory complications associated with 01 including pneumonia, the most common cause of mortality in the severe forms of the disease. We present a case of an infant with OI (type III/IV) and significant tracheobronchomalacia who had required multiple hospitalizations for recurrent atelectasis and respiratory failure in the setting of acute respiratory infections. External chest percussion and vibration were avoided because of the risk of rib fractures. intrapulmonary percussive ventilation (IPV) was initiated during an acute illness with good effect, and continued successfully after discharge from hospital. We conclude that IPV represents a safe and effective alternative to airway clearance in infants with OI. Pediatr Pulmonol. 2009; 44:1151-1154.

• 出版日期2009-11