A manganese/copper bimetallic catalyst for C-N coupling reactions under mild conditions in water

作者：Teo Yong Chua^*; Yong Fui Fong; Lim Gina Shiyun

来源：Tetrahedron Letters, 2011, 52(52): 7171-7174.

DOI：10.1016/j.tetlet.2011.10.128

• Manganese
• Copper
• Bimetallic
• Coupling
• N-arylation

An efficient and convenient bimetallic MnF2/CuI catalyst in combination with trans-1,2-diaminocyclo-hexane has been developed for the cross-coupling of nitrogen heterocycles with aryl halides in water at moderate temperature. A variety of nitrogen nucleophiles including pyrazole, 7-azaindole, indazole, indole, pyrrole and imidazole afforded the corresponding products in moderate to good yields (up to 94%) under the described arylation conditions.

• 出版日期2011-12-28
• 单位南阳理工学院