A new triterpenoid saponin and an oligosaccharide isolated from the fruits of Sapindus mukorossi

作者:Zhang, Xuan Ming; Yang, De Po; Xie, Zhi Yong; Xue, Xue; Zhu, Long Ping; Wang, Dong Mei; Zhao, Zhi Min*
来源:Natural Product Research, 2014, 28(14): 1058-1064.
DOI:10.1080/14786419.2014.905559

摘要

A new triterpenoid saponin (1) and a new oligosaccharide (2), together with three known saponins (3-5), have been isolated from n-BuOH extract of the fruits of Sapindus mukorossi Gaertn. The structures were elucidated using detailed analysis of one- and two-dimensional nuclear magnetic resonance spectra along with their mass spectrometric data and the results of acid hydrolysis. Of the isolated compounds 1 and 3-5 displayed cytotoxic effects against human cancer cell lines in A-549 (lung carcinoma), MDA-231 (breast carcinoma) and PC-3 (prostatic carcinoma).