Assessing the intracellular fate of rhodium(II) complexes

作者：Minus Matthew B; Kang Marci K; Knudsen Sarah E; Liu Wei; Krueger Michael J; Smith Morgen L; Redell Michele S; Ball Zachary T^*

来源：Chemical communications, 2016, 52(78): 11685-11688.

DOI：10.1039/c6cc05192h

Rhodium(II)-fluorophore conjugates have strong rhodium-based fluorescence quenching that can be harnessed to report on a conjugate's cellular uptake and the intracellular decomposition rate. Information gleened from this study allowed the design of an improved STAT3 metalloinhibitor.

• 出版日期2016-10-7