Nickel-Catalyzed Cycloaddition of o-Arylcarboxybenzonitriles and Alkynes via Cleavage of Two Carbon-Carbon sigma Bonds

作者：Nakai Kenichiro; Kurahashi Takuya^*; Matsubara Seijiro

来源：Journal of the American Chemical Society, 2011, 133(29): 11066-11068.

DOI：10.1021/ja203829j

An intermolecular cycloaddition reaction has been developed, where o-arylcarboxybenzonitriles react with alkynes to afford coumarins in the presence of Ni(0)/P(CH(2)Ph)(3)/MAD as a catalyst. The reaction process displays an unusual mechanistic feature the cleavage of two independent C-CN and C-CO bonds.

• 出版日期2011-7-27