Development of ovarian cancer after excision of endometrioma

作者：Haraguchi Hirofumi; Koga Kaori; Takamura Masashi; Makabe Tomoko; Sue Fusako; Miyashita Mariko; Urata Yoko; Izumi Gentaro; Harada Miyuki; Hirata Tetsuya; Hirota Yasushi; Wada Hiraike Osamu; Oda Katsutoshi; Kawana Kei; Fujii Tomoyuki; Osuga Yutaka

来源：Fertility and Sterility, 2016, 106(6): 1432-+.

DOI：10.1016/j.fertnstert.2016.07.1077

• Cancer
• cystectomy
• endometriosis
• ovary

Objective: To determine the prevalence rate of subsequent development of ovarian cancer after excision of endometrioma.
Design: Retrospective cross-sectional study.
Setting: University hospital.
Patient(S): A total of 485 women with endometrioma.
Intervention(s): Excisions of endometrioma were performed between 1995 and 2004. Data were collected from medical records in 2013.
Main Outcome Measure(s): Age, revised American Society for Reproductive Medicine score, cyst diameter, follow-up periods, endometrioma recurrence, and development of ovarian cancer.
Result(s): Recurrence of endometrioma was recorded in 121 patients (24.9% of the entire cohort), and 4 patients (0.8% of the entire cohort) developed ovarian cancer. All ovarian cancers developed from a recurrent endometrioma (3.3% of patients who experienced recurrence). Recurrence of endometrioma was significantly associated with ovarian cancer development.
Conclusion(s): Ovarian cancers can develop after excision of endometrioma and are more likely to arise from recurrent endometrioma. Special care such as rigorous follow-up should be practiced to manage patients who experience recurrence of endometrioma.

• 出版日期2016-11