A novel and photostable pH probe for selectively staining nuclei in living cells

作者:Zeng Lintao*; Fan Ne; Zha Jiayu; Hu Xichao; Fu Boqiao; Qina Caiqin; Wang Liang
来源:Analyst, 2013, 138(23): 7083-7086.
DOI:10.1039/c3an01655b

摘要

A novel pH probe based on hemi-cyanine was synthesized, which displays extremely large Stokes shift ( 122 nm) and good photostability. The probe responds to basic pH ( pK(a) 8.32) with a colorimetric and fluorescence turn-on signal. Interestingly, the probe has good cell membrane permeability and could selectively stain nuclei in living cells.