Utility of maximum perfusion intensity as an ultrasonographic marker of intraneural blood flow

作者：Borire Adeniyi A; Visser Leo H; Padua Luca; Colebatch James G; Huynh William; Simon Neil G; Kiernan Matthew C; Krishnan Arun V^*

来源：Muscle & Nerve, 2017, 55(1): 77-83.

DOI：10.1002/mus.25200

• carpal tunnel syndrome
• cross-sectional area
• intraneural blood flow
• maximum perfusion intensity
• ultrasound

We quantified intraneural blood flow (INBF) using perfusion measurement software (PixelFlux), and compared it with the qualitative method of counting blood vessels (vessel score) in a cohort of carpal tunnel syndrome (CTS) patients. Methods: Forty-seven patients (67 wrists) with a clinical and electrophysiological diagnosis of CTS, and 20 healthy controls (40 wrists) were enrolled. Median nerve ultrasound (US) was performed at the carpal tunnel inlet to measure the cross-sectional area (CSA) and vessel score. Power Doppler sonograms from nerves with detectable INBF were processed with PixelFlux to obtain the maximum perfusion intensity (MPI). Results: Forty-nine percent of CTS patients had detectable INBF compared with none in the control group (P<0.0001). MPI correlated significantly with vessel score (r=0.945, P<0.0001), CSA (r=0.613, P<0.0001), and electrophysiological severity (r=0.440, P<0.0001). MPI had higher intra- or interobserver reliability compared with vessel score (0.95 vs. 0.47). Conclusion: MPI is a better method for quantification of INBF. Muscle Nerve, 2016 Muscle Nerve55: 77-83, 2017

• 出版日期2017-1