Anthelmintic effect of Cassia fistula and Combretum leprosum protein fractions against goat gastrointestinal nematodes

作者：de Oliveira Silva Mara Thais; Colares Maia Mara Andrade; Correia da Silva Michele Dalvina; Torres Taffarel Melo; da Silveira Pereira Jose Carlos; Campelo Araujo Joao Ronielly; da Silva Ryan Emiliano; da Costa Souza Anna Lopes; Barbosa Tallyson Nogueira; Diogenes Suassuna Bezerra Ana Carla

来源：REVISTA BRASILEIRA DE PARASITOLOGIA VETERINARIA, 2018, 27(2): 237-241.

DOI：10.1590/S1984-296120180041

• Phytotherapy
• Cassia fistula L.
• Combretum leprosum Mart
• larvicidal activity
• ovicidal activity

In this study, we evaluated the ovicidal and larvicidal activity of protein preparations obtained from Cassia fistula L. and Combretum leprosum Mart. leaves on the gastrointestinal parasites of goats. Protein preparations were obtained after the extraction of C. fistula L. and C. leprosum Mart. leaves, followed by protein fractionation (with ammonium sulfate saturation percentages of 30%, 30%-60%, and 60%-90%) and dialysis, which resulted in protein fractions (called F1, F2, and F3, respectively). The fractions were evaluated by egg hatching (the eggs were recovered in stool samples from naturally infected goats) and larval development tests. The results reveled that the inhibition of hatching of eggs caused by the protein fractions of C. fistula (38%) were similar to that of the control drug, thiabendazole. In addition, the fractions of C. fistula caused significant inhibition (61-69%) of larval development also. However, C. leprosum did not reveal significant inhibition of egg hatching and larval development. We conclude that C. fistula L. showed better ovicidal and larvicidal activity against endoparasites.

• 出版日期2018-6