Dynamic modulation of detection window in conducting polymer based biosensors

作者：Choong Chwee Lin^*; Milne William I

来源：Biosensors and Bioelectronics, 2010, 25(10): 2384-2388.

DOI：10.1016/j.bios.2010.03.023

• Biosensor
• Conducting polymer
• Tunable detection window
• Molecular imprinted polymer
• Electrical stimuli

Here we demonstrate a novel application that employs the ion exchange properties of conducting polymers (CP) to modulate the detection window of a CP based biosensor under electrical stimuli. The detection window can be modulated by electrochemically controlling the degree of swelling of the CF associated with ion transport in and out of the polymer. We show that the modulation in the detection window of a caffeine imprinted polypyrrole biosensor, and by extension other CP based biosensors, can be achieved with this mechanism. Such dynamic modulation in the detection window has great potential for the development of smart biosensors, where the sensitivity of the sensor can be dynamically optimized for a specific test solution.

• 出版日期2010-6-15