Antibacterial applications of alpha-Fe2O3/Co3O4 nanocomposites and study of their structural, optical, magnetic and cytotoxic characteristics

作者：Bhushan Mayank; Kumar Yogesh; Periyasamy Latha; Viswanath Annamraju Kasi

来源：Applied Nanoscience, 2018, 8(1-2): 137-153.

DOI：10.1007/s13204-018-0656-5

<jats:title>Abstract</jats:title>
<jats:p>Owing to their multiple mechanisms of bactericidal activity, inorganic metal oxides and hybrid metal oxide nanocomposites may serve as a new class of effective disinfectants. Among metal oxide nanoparticles, iron oxide nanoparticles exhibit minimal or no cytotoxicity to human cells with very efficient bactericidal properties over a wide spectrum of bacteria. This paper presents the very first report on antibacterial properties of novel nanocomposites of iron oxide and cobalt oxide nanoparticles against pathogenic bacterial strains <jats:italic>B. subtilis</jats:italic>, <jats:italic>S. aureus</jats:italic>, <jats:italic>E.coli</jats:italic> and <jats:italic>S. typhi</jats:italic>. The enhanced bactericidal activity of the Fe/Co oxide nanocomposite was the result of synergistic effect of iron oxide and cobalt oxide nanoparticles. The nanocomposites were synthesized using co-precipitation route with increasing cobalt content in the sample and further characterized using XRD, TEM, Raman and VSM to investigate structural, optical and magnetic properties of the prepared nanocomposites, respectively. Also, the prepared nanocomposites were highly biocompatible and found non-toxic to human cell line MCF7.</jats:p>

• 出版日期2018-2