Determination of the Five Main Terpenoids in Different Tissues of Wolfiporia cocos

作者：Fu, Ming; Wang, Li; Wang, Xianyou; Deng, Boxia; Hu, Xing^*; Zou, Juan^*

来源：Molecules, 2018, 23(8): 1839.

DOI：10.3390/molecules23081839

• Wolfiporia cocos
• triterpenoids
• pollution-controlled cultivation
• sclerotium
• fruiting body

Wolfiporia cocos is a fungus containing triterpenoids and is widely used as an herbal medicine. However, it is unknown whether its main triterpenoid contents differ in different tissues. In this study, we identified dehydrotumulosic acid, polyporenic acid C, pachymic acid, dehydrotrametenolic acid, and dehydroeburicoic acid as the five main triterpenoids in W. cocos. We also systematically profiled the contents and distribution of these main triterpenoids in different tissues of W. cocos. High contents of all five triterpenoids were found in the surface layer of W. cocos. Intriguingly, we noted that the highest contents of the five triterpenoids were found in the surface layer of the sclerotium grown under pollution-controlled cultivation; the second-highest contents were found in the surface layer of the natural sclerotium. These results indicate that environmentally friendly cultivation of the sclerotium of W. cocos is a practical way to increase the productivity of W. cocos. In addition, our findings suggest that the triterpenoids may contribute to the pharmacological activity of W. cocos, and the surface layer of sclerotium in W. cocos might be a promising raw material for applications in health care and the development of functional medical products.

• 出版日期2018-8
• 单位怀化学院