A multi-step peptidolytic cascade for amino acid recovery in chloroplasts

作者:Teixeira, Pedro F.*; Kmiec, Beata; Branca, Rui M. M.; Murcha, Monika W.; Byzia, Anna; Ivanova, Aneta; Whelan, James; Drag, Marcin; Lehtio, Janne; Glaser, Elzbieta
来源:Nature Chemical Biology, 2017, 13(1): 15-17.
DOI:10.1038/NCHEMBIO.2227

摘要

Plastids (including chloroplasts) are subcellular sites for a plethora of proteolytic reactions, required in functions ranging from protein biogenesis to quality control. Here we show that peptides generated from pre-protein maturation within chloroplasts of Arabidopsis thaliana are degraded to amino acids by a multi-step peptidolytic cascade consisting of oligopeptidases and aminopeptidases, effectively allowing the recovery of single amino acids within these organelles.

  • 出版日期2017-1