Analysis of the VP2 protein gene of canine parvovirus strains from affected dogs in Japan

作者：Soma Takehisa^*; Taharaguchi Satoshi; Ohinata Tsuyoshi; Ishii Hiroshi; Hara Motonobu

来源：Research in Veterinary Science, 2013, 94(2): 368-371.

DOI：10.1016/j.rvsc.2012.09.013

• Canine parvovirus 2
• Dog
• Japan
• Sequence
• VP2

To clarify the evolution of canine parvovirus 2 (CPV-2) that has recently been epidemic in Japan, VP2 gene sequences at positions 3556-4166 were analyzed in 107 CPV-2 strains obtained from rectal swabs of diarrheic dogs from 2009 to 2011. CPV-2b (95 strains) was more frequently detected than CPV-2a (nine strains), while CPV-2c was not detected. Remaining three strains were identified as the original type CPV-2, which should be derived from vaccines. These findings are similar to the previous results involving Japanese strains, suggesting there has been no great change in the recent CPV-2 epidemic in Japan. This epidemic is the same as that in Taiwan. Furthermore, a 324-lle mutant, which has been reported in Korean and Chinese strains, was detected in 66.7% of CPV-2a strains.

• 出版日期2013-4