Diarylheptanoids from the fresh pericarps of Juglans sigillata

作者:Liang, Jingjing; Peng, Xiaogang; Zhou, Jia; Zhou, Ming; Ruan, Hanli*
来源:Natural Product Research, 2018, 32(20): 2457-2463.
DOI:10.1080/14786419.2017.1419235

摘要

One new diarylheptanoid (3S)-3', 4 ''-epoxy-1-(4'-hydroxylphenyl)-7-(3.-hydroxylphenyl) heptane-3-hydroxy (1), together with eleven known ones (2-12), was isolated from the fresh pericarps of Juglans sigillata. Their structures were elucidated on the basis of extensive spectroscopic methods, including HR-ESI-MS, 1D and 2D-NMR. All isolates were evaluated for their cytotoxic activities in vitro against the growth of human cancer cells lines HT-29 and MCF-7 by MTT assay. @@@ [GRAPHICS] @@@ .