A New Long-Chain Alkene and Antituberculosis Constituents from the Leaves of Pourthiaea lucida

作者:Chen Jih Jung*; Lin Wen Jiou; Shieh Po Chuen; Chen Ih Sheng; Peng Chien Fang; Sung Ping Jyun
来源:Chemistry and Biodiversity, 2010, 7(3): 717-721.

摘要

A new long-chain alkene, dotriacont-1-ene (1), was isolated from the leaves of Pourthiaea lucida, together with twelve known compounds. The structure of this new compound was determined by NMR and mass-spectrometric analyses. Among the isolated compounds, alpha-tocospiro A (2), alpha-tocopheryl quinone (4), and (E)-phytol (5) exhibited antituberculosis activities (MICs <= 30 mu g/ml) against Mycobacterium tuberculosis H(37)Rv in vitro.

  • 出版日期2010