摘要

Objective: We describe a method to measure oxygen consumption (VO2) and pulmonary vascular resistive index (PVRI) based on thermodilution cardiac output in patients with complex mixing circulations. We apply this method to patients with a bidirectional cavopulmonary anastomosis (BDCPA). We compare our measured VO2 with a predicted VO2 based on a formula using height and weight. %26lt;br%26gt;Methods: We reviewed data based on cardiac catheterization and thermodilution cardiac output in a series of 25 catheterizations in patients with BDCPA. We used this data to measure VO2 and PVRI, and looked for a correlation between the predicted and measured VO2. We also assessed whether any other hemodynamic parameter correlated with measured VO2. %26lt;br%26gt;Results: There was no significant correlation between the predicted and the measured VO2 (correlation coefficient = -0.258, P= .21). We did find a significant correlation in the difference between the measured and predicted VO2 against the measured VO2 such that at a lower measured VO2 the predictive formula tended to overestimate VO2 and at a higher VO2 the formula underestimated VO2 (correlation coefficient = 0.963, P %26lt;. 0001). Body surface area did not correlate with measured VO2 (correlation coefficient = 0.28, P %26lt;. 16). Mixed venous oxygen content showed a weak negative correlation with VO2 (correlation coefficient = -0.54, P = .005). %26lt;br%26gt;Conclusions: An assessment of PVRI that is based on a predicted VO2 is unreliable in this patient population. No hemodynamic parameter correlated well with VO2. The use of a measured VO2 is necessary in determining PVRI in these patients.

  • 出版日期2013-11

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