Usefulness of F-18-fluorodeoxyglucose Positron Emission Tomography as Predictor of Distant Metastasis in Preoperative Carbon-ion Radiotherapy for Pancreatic Cancer

作者：Shinoto Makoto^*; Yamada Shigeru; Yoshikawa Kyosan; Yasuda Shigeo; Shioyama Yoshiyuki; Honda Hiroshi; Kamada Tadashi; Tsujii Hirohiko

来源：Anticancer Research, 2013, 33(12): 5579-5584.

• FDG-PET
• carbon-ion radiotherapy
• preoperative
• distant metastasis
• prognostic factor

Aim: The purpose of this study was to evaluate the role of FDG-PET regarding the indication of preoperative carbon-ion radiotherapy (GIRT) for pancreatic cancer patients. Patients and Methods: Patients with resectable pancreatic cancer underwent preoperative CIRT. The impact of baseline SUVmax on prognosis for patients was assessed by analyzing correlations with distant metastasis-free survival (DMFS) and overall survival (OS). Results: Out of 21 patients, local recurrence was observed in no patient and distant metastasis was found in 13 patients (62%). 1-year DMFS and OS in low-SUVmax group were significantly higher than those in high-SUVmax group (91% vs. 20% and 91% vs. 56%). SUVmax was significantly correlated with DMFS and OS. Conclusion: Our data indicated a significant correlation between SUVmax and DMFS. FDG-PET might be useful for determining the indication of preoperative short-course CIRT for patients with resectable pancreatic cancer.

• 出版日期2013-12