ACCELERATOR PRODUCTION AND NUCLEAR ASPECTS OF Y-88: AN EFFICIENT RADIOTRACER

作者:Enferadi Milad*; Sadeghi Mahdi; Bolourinovin Fatemeh
来源:Nuclear Technology & Radiation Protection, 2011, 26(3): 201-208.
DOI:10.2298/NTRP1103201E

摘要

Yttrium-88 (T-1/2 = 106.6 d, I beta+ = 0.2% and I-EC = 99.8%) is used in mixed gamma efficiency calibration standards and also as a substitute for Y-90 to quantify the biodistribution of Y-pharmaceuticals in animals. Yttrium-88 and strontium-85 as gamma emitting radiotracers were produced via (SrCO3)-Sr-nat(p, xn) and (RbCl)-Rb-nat(p, xn) nuclear processes at AMIRS, with 18 and 15 MeV protons, respectively, at a current of 20 mu A for 10 hours. The deposition of (SrCO3)-Sr-nat on the Cu backing was carried out by means of the sedimentation method. Yttrium-88 was separated in a 92 +/- 5% radiochemical yield using the precipitation technique by precipitating Sr-nat as SrSO4 (strontium-85 as a tracer) while radioyttrium passed through the filter paper. Also, a theoretical study of the nuclear reaction cross-sections for proton and deuteron induced reactions on Sr-nat and Rb-nat for the production of Y-88 and Sr-85, respectively, was performed using the EMPIRE (version 3.1 Rivoli), TALYS-1.26 codes and the TENDL-2010 database.

  • 出版日期2011-12