An Antibacterial Zn-MOF with Hydrazinebenzoate Linkers

作者:Restrepo Jimmy; Serroukh Zakarias; Santiago Morales Javier; Aguado Sonia; Gomez Sal Pilar*; Mosquera Marta E G*; Rosal Roberto
来源:European Journal of Inorganic Chemistry, 2017, 2017(3): 574-580.
DOI:10.1002/ejic.201601185

摘要

A Zn-based metal-organic framework (MOF) with hydrazinebenzoate linkers was evaluated as antimicrobial material against the Gram-positive bacterium Staphylococcus aureus. The material inhibits bacterial growth and metabolic activity, with a half maximal effective concentration of about 20 mg L-1 material dispersed in the culture medium. The antimicrobial effect can be attributed to the release of the 4-hydrazinebenzoate linker, with a negligible contribution from the free metal. The material exhibits remarkable durability, and it enables the sustained release of the ligand over a period of several days.

  • 出版日期2017-1