A biocompatible process to prepare hyaluronan-based material able to self-assemble into stable nano-particles

作者:Calce Enrica; Ringhieri Paola; Mercurio Flavia Anna; Leone Marilisa; Bugatti Valeria; Saviano Michele; Vittoria Vittoria; De Luca Stefania*
来源:RSC Advances, 2015, 5(37): 29573-29576.
DOI:10.1039/c5ra03107a

摘要

New self-assembled nano-particles were developed by chemical conjugation of natural fatty acids to the backbone of hyaluronan (HA). The chemical structure and the self-association behavior of them were studied by FT-IR, NMR, fluorescence and dynamic light scattering. The HA derivatives form stable spherical shape aggregates, as assessed by transmission electron microscopy.

  • 出版日期2015