Granulosa Cell Tumors of the Ovary and Inhibin B

作者:Lyubimova N V*; Beyshembaev A M; Kushlinskiy D N; Zordania K I; Adamyan L V
来源:Bulletin of Experimental Biology and Medicine, 2011, 150(5): 635-638.

摘要

We present the results of immunoenzyme detection of inhibin B in blood serum of patients with adult-type granulosa cell tumors of the ovary. Blood concentration of inhibin B at the end of menstrual cycle in patients with tumor relapse was significantly higher than in patients during remission and in virtually healthy women. The increase in inhibin B concentration preceded clinical manifestation of the disease relapse by 2-13 months, which demonstrates high diagnostic sensitivity of this marker and suggests that it can be recommended for the use in diagnostics and monitoring of granulosa cell tumors of the ovaries.

  • 出版日期2011-3