FeSO4-promoted direct arylation of benzoquinones with ArB(OH)(2) or ArBF3K

作者：Komeyama Kimihiro^*; Kashihara Tetsuya; Takaki Ken

来源：Tetrahedron Letters, 2013, 54(9): 1084-1086.

DOI：10.1016/j.tetlet.2012.12.031

• Iron salt
• Direct arylation
• Benzoquinones
• Aryl boronic acids
• Electron transfer reaction

FeSO4 center dot 7H(2)O was proven to work as effective promoter for the direct arylation of benzoquinones with aryl boronic acids in the presence of K2S2O8. In the arylation, slow addition of iron solution was crucial to efficiently proceed with the reaction. Interestingly, the Fe-mediated arylation could be converted into a catalytic reaction by using hydroquinones, instead of benzoquinones, or addition of ascorbic acid.

• 出版日期2013-2-27