Donor quality of life after living donor liver transplantation: a prospective study

作者：Togashi Junichi; Sugawara Yasuhiko^*; Tamura Sumihito; Yamashiki Noriyo; Kaneko Junichi; Aoki Taku; Hasegawa Kiyoshi; Beck Yoshifumi; Makuuchi Masatoshi; Kokudo Norihiro

来源：Journal of Hepato-Biliary-Pancreatic Sciences, 2011, 18(2): 263-267.

DOI：10.1007/s00534-010-0340-y

• Quality of life
• Health-related quality of life
• Donor
• Living donor liver transplantation
• SF-36v2

It is important to determine the health-related quality of life of live donors in liver transplantation.
We reviewed 35 live liver donors and prospectively and longitudinally evaluated their health-related quality for 1.5 years post-surgery based on the Short Form-36 version 2 questionnaire. Scores of the donors stratified by the clinical data were analyzed. The study was approved by the University of Tokyo Institutional Review Board (No. 1533).
There was no donor mortality in the donor population studied. The percentage of major complications greater than Clavien's classification grade III was 8.6%. The physical component summary score decreased to 42.9 (p < 0.01) at 3 months, but recovered within 6 months after the operation. The mental component summary scores did not change during the observation period. The stratification study revealed that age and postoperative complications remained significant factors among the high physical component summary scores 3 months after the operation.
The findings from this survey suggest that liver harvesting does not decrease the donor's quality of life during the 1.5 years following the surgery.

• 出版日期2011-3