Allograft bone matrix versus synthetic bone graft substitutes

作者：Zimmermann Gerald^*; Moghaddam Arash

来源：Injury-International Journal of the Care of the Injured, 2011, 42: S16-S21.

DOI：10.1016/j.injury.2011.06.199

• Synthetic bone substitutes
• Bone morphogenetic protein
• Demineralized bone matrix
• Allograft

Autologous bone is used very often in the treatment of fresh fractures, delayed unions and non-unions. Alternatives have included allografts and in recent years also demineralized bone matrix. The growing availability of good synthetic bone grafts and their advantages in safety and avoiding donor-site morbidity are the reasons that these products are being used more and more. There are on the market a wide variety of substitutes with different capabilities. Nevertheless autologous bone graft is still considered as the gold standard and will be discussed here in that context. Osteoconductive, osteogenic and osteoinductive products will also be classified and their advantages and disadvantages described.

• 出版日期2011-9