A duplex PCR method to identify mosaic penA gene and predict reduced susceptibility to oral cephalosporins in Neisseria gonorrhoeae

作者：Huang Chung Ter; Niu Jennifer; Liao Mei Hui; Li Shu Ying^*

来源：Journal of Microbiological Methods, 2010, 83(2): 257-259.

DOI：10.1016/j.mimet.2010.08.011

• Neisseria gonorrhoeae
• Mosaic PBP2
• Cephalosporin susceptibility

Neisseria gonorrhoeae with mosaic penicillin-binding protein 2 (PBP2) is associated with reduced susceptibility to third-generation oral cephalosporins. A simple and rapid PCR method using three primers was designed to identify mosaic PBP2, which could help predict reduced susceptibility to expanded-spectrum cephalosporins in N. gonorrhoeae.

• 出版日期2010-11