Automatic detection and resolution of measurement-unit conflicts in aggregated data

作者：Samadian Soroush; McManus Bruce; Wilkinson Mark D^*

来源：BMC Medical Genomics, 2014, 7(Suppl 1): S12.

DOI：10.1186/1755-8794-7-S1-S12

Background: Measurement-unit conflicts are a perennial problem in integrative research domains such as clinical meta-analysis. As multi-national collaborations grow, as new measurement instruments appear, and as Linked Open Data infrastructures become increasingly pervasive, the number of such conflicts will similarly increase. %26lt;br%26gt;Methods: We propose a generic approach to the problem of (a) encoding measurement units in datasets in a machine-readable manner, (b) detecting when a dataset contained mixtures of measurement units, and (c) automatically converting any conflicting units into a desired unit, as defined for a given study. %26lt;br%26gt;Results: We utilized existing ontologies and standards for scientific data representation, measurement unit definition, and data manipulation to build a simple and flexible Semantic Web Service-based approach to measurement-unit harmonization. A cardiovascular patient cohort in which clinical measurements were recorded in a number of different units (e. g., mmHg and cmHg for blood pressure) was automatically classified into a number of clinical phenotypes, semantically defined using different measurement units. %26lt;br%26gt;Conclusions: We demonstrate that through a combination of semantic standards and frameworks, unit integration problems can be automatically detected and resolved.

• 出版日期2014-5-8