A unifying experimental design for dissecting tree genomes

作者:Sun Lidan; Zhu Xuli; Zhang Qixiang; Wu Rongling*
来源:Trends in Plant Science, 2015, 20(8): 473-476.
DOI:10.1016/j.tplants.2015.05.012

摘要

Linkage mapping and association mapping are adopted as an approach of choice for dissecting complex traits, but each shows a limitation when used alone. We propose an open-pollinated (OP) family design to integrate these two approaches into an organizing framework. The design unifies the strengths of population and quantitative genetic studies for evolutionary inference and high-resolution gene mapping. It particularly suits genome dissection of forest trees given their extant populations that are mostly undomesticated.