Amino group binding peptide aptamers with double disulphide-bridged loops selected by in vitro selection using cDNA display

作者：Mochizuki Yuki; Nishigaki Koichi; Nemoto Naoto^*

来源：Chemical communications, 2014, 50(42): 5608-5610.

DOI：10.1039/c4cc00799a

Peptide aptamers that specifically bind to the amino group on a solid-phase were screened by in vitro selection using the cDNA display method. The identified peptides have a unique structure containing two cyclic loops with disulphide bonds and a linkage region, which were indispensable for molecular recognition.

• 出版日期2014