Asymmetric Cycloisomerization of 1, n-Enynes Catalyzed by Transition Metals

作者：Chen Mao; Weng Yue; Lei Aiwen^*

来源：Progress in Chemistry, 2010, 22(7): 1341-1352.

• transition metal catalysis
• cycloisomerization
• enynes
• asymmetric reactions

Asymmetric cycloisomerization catalyzed by transition metals, which possesses highly catalytic activity and good selectivity, is a potential protocol to fulfill the goal of "atom economy". In recent years, impressive achievements have been made in this area. It becomes one of the most efficient methods to synthesize enantiomeric pure carbon- or heterocyclic compounds. This paper summarized the development of transition metal catalyzed asymmetric cycloisomerization in recent twenty years and briefly reviewed its applications in total synthesis of natural products.

• 出版日期2010-7
• 单位武汉大学