Agitation thrombolysis and catheter-directed thrombolysis for normotensive patients with acute pulmonary thromboembolism

作者：Bi, Yonghua; Yu, Zepeng; Han, Xinwei^*; Ren, Jianzhuang

来源：Radiologia Medica, 2018, 123(5): 338-344.

DOI：10.1007/s11547-017-0848-1

• Pulmonary thromboembolism
• Agitation thrombolysis
• Catheter-directed thrombolysis
• Thrombolysis
• Follow-up

To assess the feasibility, efficacy, and safety of agitation thrombolysis and catheter-directed thrombolysis (AT-CDT) in the treatment of normotensive patients with acute pulmonary thromboembolism (PTE).
A total of 37 consecutive patients of normotensive PTE were treated by AT-CDT between October 2011 and January 2016. Clinical outcomes and mortality were evaluated after the treatment, and follow-up was carried out after hospital discharge.
AT-CDT was technically successful in 93.7% (36/37) patients, with one case died from respiratory failure during procedure. The clinical success rate was 91.9% (34/37), one patient died from intracranial hemorrhage 9 days after agitation, and one case showed no improvement. A total of 83.8% (31/37) cases were clinical cured and 8.1% (3/37) cases were relieved during hospitalization. Three cases died of respiratory failure caused by PTE, and two cases died of diseases unrelated to PTE (lung carcinoma/hemoptysis) during a 20-1524 days of follow-up.
AT-CDT may be a feasible, effective, and safe treatment for normotensive patients with acute PTE.

• 出版日期2018-5
• 单位郑州大学