Novel synthesis of 3-aminopropionitriles by ring opening of 2-oxazolidinones with cyanide ion

作者:Taniguchi Tsuyoshi; Goto Naoya; Ishibashi Hiroyuki*
来源:Tetrahedron Letters, 2009, 50(34): 4857-4858.
DOI:10.1016/j.tetlet.2009.06.014

摘要

Nucleophilic attack of cyanide ion on the 5-position of 2-oxazolidinones in the presence of 18-crown-6 gave 3-aminopropionitriles.