Antibacterial activities of zinc oxide nanoparticles against Escherichia coli O157:H7

作者：Liu Y; He L; Mustapha A; Li H; Hu Z Q; Lin M^*

来源：Journal of Applied Microbiology, 2009, 107(4): 1193-1201.

DOI：10.1111/j.1365-2672.2009.04303.x

• antibacterial activity
• E
• coli O157:H7
• nanoparticles
• Raman
• zinc oxide

Aims:
To investigate antibacterial activities of zinc oxide nanoparticles (ZnO NP) and their mode of action against an important foodborne pathogen, Escherichia coli O157:H7.
Methods and Results:
ZnO NP with sizes of 70 nm and concentrations of 0, 3, 6 and 12 mmol lConclusions:
ZnO NP were found to have antibacterial activity against E. coli O157:H7. The inhibitory effects increase as the concentration of ZnO NP increased. Results indicate that ZnO NP may distort and damage bacterial cell membrane, resulting in a leakage of intracellular contents and eventually the death of bacterial cells.
Significance and Impact of the Study:
These results suggest that ZnO NP could potentially be used as an effective antibacterial agent to protect agricultural and food safety.

• 出版日期2009-10