Antibacterial and Antifungal ActivitiesSurface Active Properties Relation of Novel Dischiff Base Cationic Gemini Amphiphiles Bearing Homogeneous Hydrophobes

作者：Negm Nabel A^*; Zaki Mohamed F; Salem Mounir A I

来源：Journal of Dispersion Science and Technology, 2010, 31(10): 1390-1395.

DOI：10.1080/01932690903269784

• Antibacterial activity
• antifungal activity
• critical micelle concentration
• effectiveness
• efficiency
• gemini surfactants
• maximum surface excess
• minimum surface area
• sulfur reducing bacteria
• surface activity

A novel series of cationic Gemini amphiphiles containing Dischiff base species were synthesized and their chemical structures were determined using different analytical tools. Their surface properties were determined using surface tension measurements. The adsorption and micellization thermodynamic parameters were calculated using Gibb's equations at 25 degrees C. The surface parameters were also determined including critical micelle concentration, effectiveness, efficiency, maximum surface excess, minimum surface area, interfacial tension, and emulsification power. The synthesized cationic Gemini surfactants were evaluated as bactericides for gram negative and gram positive bacteria and also against sulfur reducing bacteria (SRB). The results of the cytotoxicity of the synthesized compounds against the targeted bacterial strains were promising and completely dependent on the surface activity of these compounds.

• 出版日期2010