ANGIOGRAPHIC SUBTYPES OF POLYPOIDAL CHOROIDAL VASCULOPATHY IN TAIWAN A Prospective Multicenter Study

作者：Yeung Ling; Kuo Chien-Neng; Chao An-Ning; Chen Kuan-Jen; Wu Wei-Chi; Lai Chien-Hsiung^*; Wang Nan-Kai; Hwang Yih-Shiou; Chen Ching-Lung; Lai Chi-Chun^*

来源：Retina-The Journal of Retinal and Vitreous Diseases, 2018, 38(2): 263-271.

• age-related macular degeneration
• choroidal neovascularization
• polypoidal choroidal neovascularization
• polypoidal choroidal vasculopathy
• retinal angiomatous proliferation

Purpose: To determine the incidence and clinical characteristics of angiographic subtypes of polypoidal choroidal vasculopathy (PCV).
Methods: It is a prospective, multicenter, cross-sectional study. Patients with newly diagnosed exudative macular degeneration are classified into PCV, age-related macular degeneration (AMD), and retinal angiomatous proliferation. Polypoidal choroidal vasculopathy is further classified into two subtypes depending on the presence (Type 1: polypoidal choroidal neovascularization) or absence (Type 2: typical PCV) of feeder vessels on indocyanine green angiography.
Results: We enrolled 169 patients: 76 (45%) with PCV, 75 (44.4%) with AMD, and 14 (8.3%) with retinal angiomatous proliferation. Of the patients with PCV, 20 (26%) were classified as Type 1 PCV and 56 (74%) were classified as Type 2 PCV. The Type 1 PCV had a similar mean age compared to the AMD group (73.1 +/- 9.6 vs. 75.6 +/- 8.8 years, P = 0.281) and the Type 2 PCV (68.8 +/- 9.6 years) was younger than the AMD group (P, 0.001). Type 1 PCV presented with worse visual acuity compared with the AMD. Both PCV subtypes had a higher incidence of hemorrhagic complications (85% and 75% respectively).
Conclusion: Type 2 PCV is more common than Type 1 PCV in Taiwan. Our results support the hypothesis that polypoidal choroidal neovascularization and typical PCV may be distinct entities.

• 出版日期2018-2
• 单位长春大学