Methylating mushrooms

作者:Bowers Albert A*
来源:Nature Chemical Biology, 2017, 13(8): 821-822.
DOI:10.1038/nchembio.2437

摘要

The genome of the poisonous mushroom Omphalotus olearius provides a potent new biocatalytic strategy for installing backbone N-methyl amides on ribosomally synthesized peptides. This discovery could yield new biotechnologies for drug development from peptide macrocycles.

  • 出版日期2017-8