Antimicrobial activities of Gloriosa superba Linn (Colchicaceae) extracts

作者：Khan Haroon; Khan Murad Ali^*; Mahmood Tahira; Choudhary Muhammad Iqbal

来源：Journal of Enzyme Inhibition and Medicinal Chemistry, 2008, 23(6): 855-859.

DOI：10.1080/14756360701747409

• Gloriosa superba Linn
• antibacterial
• antifungal
• total phenol content
• rhizomes
• extracts

The methanol extract of the rhizomes of Gloriosa superba Linn (Colchicaceae) and its subsequent fractions in different solvent systems were screened for antibacterial and antifungal activities. Excellent antifungal sensitivity was expressed by the n-butanol fraction against Candida albicans and Candida glaberata (up to 90%) and against Trichophyton longifusus (78%) followed by the chloroform fraction against Microsporum canis (80%). In the antibacterial bioassay, the crude extract and subsequent fractions showed mild to moderate antibacterial activities. Chloroform fraction displayed highest antibacterial sensitivity against Staphylococcus aureous (88%) followed by the crude extract (59%). The total phenol content of the crude extract and fractions of the plant expressed no significant correlation with the antimicrobial activities.

• 出版日期2008