A novel and efficient synthesis of 2-aryl-2H-indazoles via SnCl2-mediated cyclization of 2-nitrobenzylamines

作者:Shi Da Qing*; Dou Guo Lan; Ni Sai Nan; Shi Jing Wen; Li Xiao Yue; Wang Xiang Shan; Wu Hui; Ji Shun Jun
来源:Synlett, 2007, (16): 2509-2512.
DOI:10.1055/s-2007-986665

摘要

A mild, efficient, and novel synthesis of 2-aryl-2H-indazoles via cyclization of 2-nitrobenzylamines promoted by SnC1(2)-2H(2)O has been described. This method applies to a wide scope of substrates containing electron-donating and electron-withdrawing substituents.