摘要

In this paper, we carried out a systematic chemical study on the ethyl acetate (EtOAc) extract from the flowers of Hosta plantaginea (Lam.) Aschers (H. plantaginea), which resulted in the isolation of a new compound (1) together with one known compound (2). The structure elucidations of new compound were carried out by 1D [H-1 and C-13 nuclear magnetic resonance (NMR)] and 2D-NMR spectral analysis. Studies on the antibacterial activity established that compound 1 showed statistically higher inhibition against Staphylococcus aureus (S. aureus) compared to streptomycin and compound 2. Among the tested bacteria, Bacillus cereus (B. cereus) was the most sensitive and Yersinia enterocolitica (Y. enterocolitica) was found to be the most resistant. The antibacterial activities exhibited by compound 1 demonstrate their potential for use as nutraceuticals and in food preservation. Practical applicationsThe flowers of H. plantaginea are used as a clinical medicine to treat many diseases, such as swelling, mastadenitis, otitismedia, anabrosis, lung heat, and terrific heat. Various pharmacological properties have been observed in some steroidal glycosides and alkaloids from H. plantaginea including cytotoxic and anti-inflammatory. In the article, the antibacterial activities of two monoterpene glycosides from the flowers of H. plantaginea have been evaluated for the first time. Therefore, the results may have some useful practical implications at both the food and medicine technology.