科研之友
微信
新浪微博
Facebook
分享链接
摘要
A concise synthesis of functionalized indene derivatives via the gold(I)-catalysed cascade C-H functionalization/conia-ene type reaction of electron-rich aromatics with o-alkynylaryl alpha-diazoesters has been developed. In this transformation, the gold catalyst not only catalysed the formation of the zwitterionic intermediate via intermolecular C-H functionalization but promoted the subsequent intramolecular 5-endo-dig cyclization via activation of alkynes. The reaction is characterized by high chemo-and site-selectivity, readily available starting materials, nice functional-group tolerance and mild reaction conditions.
- 出版日期2016
- 单位华东师范大学
