A pattern-oriented specification of gene network inference processes

作者：Trepode Nestor W; de Farias Clever R G^*; Barrera Junior

来源：Computers in Biology and Medicine, 2013, 43(10): 1415-1427.

DOI：10.1016/j.compbiomed.2013.07.008

• Genetic regulatory networks
• Dynamical system identification
• Gene network inference
• Microarray data analysis
• Process modeling
• Patterns

Patterns have been widely used in Computer Science. A pattern describes a generic solution to an existing problem in a more readable and accessible form. A pattern-oriented process specification consists of a generic and abstract description of a process. This paper presents a pattern-oriented specification of a genetic regulatory network inference process performed from microarray data and prior biological knowledge. The proposed specification was conceived based on prior work on gene inference networks. The adequacy of the proposed solution was then evaluated with respect to modern tendencies of the genes network inference literature.

• 出版日期2013-10-1