Development of High Acquisition Speed Time. of. Flight Mass Spectrometer for Combination with Comprehensive Two-dimensional Gas Chromatography

作者：Wu Man-Man; Cen Yan-Xiang; Yang Li-Hua; Qiao Jia; Gao Wei^*

来源：Chinese Journal of Analytical Chemistry, 2016, 44(11): 1786-1792.

DOI：10.11895/j.issn.0253.3820.160557

• Time-of-flight mass spectrometer
• High acquisition speed
• Electron impact ionization source
• Comprehensive two-dimensional gas chromatography

A novel time-of-flight mass spectrometer which adopted high sensitivity electron impact ionization source and orthogonal-injected two-stage-reflector mass analyzer structure was developed for the combination with comprehensive two-dimensional gas chromatography. With 20 kHz of extraction frequency, the mass detection range and mass resolution of this instrument were from 1 to 1000 amu and better than 1000 (m/z = 219, ADC card), respectively, with a detection limit of less than 1 pg and a linear range more than 4 orders of magnitude. Meanwhile the instrument has a high acquisition speed of 400 spectra per second, which made it satisfy for combination with comprehensive two-dimensional gas chromatography. For the moment, this mass spectrometer combined with the first domestic comprehensive two-dimensional gas chromatography was successfully used for the detection of many complicated samples in the field of petroleum, environment and essence, revealing its ability for connecting with the comprehensive two-dimensional gas chromatography and the application potential for full component analysis of complex system.

• 出版日期2016-11
• 单位暨南大学