Molecular fields in drug discovery: getting old or reaching maturity?

作者：Cross Simon^*; Cruciani Gabriele

来源：Drug Discovery Today, 2010, 15(1-2): 23-32.

DOI：10.1016/j.drudis.2008.12.006

With GRID first published 23 years ago, and CoMFA 20 years ago, the two most widely known methods that apply molecular fields to drug discovery are now into their third decade. Are molecular-field-based methods still applicable to modern drug discovery? Are they old and outdated? Or are they maturing into their full potential?

• 出版日期2010-1