A high performance electrochemical biosensor based on Cu2O-carbon dots for selective and sensitive determination of dopamine in human serum

作者：Huang Qitong; Lin Xiaofeng; Lin Changqing; Zhang Yong; Hu Shirong; Wei Chan

来源：RSC Advances, 2015, 5(67): 54102-54108.

DOI：10.1039/c5ra05433h

• Carbon dots
• Carboxyl groups
• Cuprous oxide
• Electrochemical biosensor
• Facile method
• Ion exchange modeling
• Low detection limit
• Wide-linear range

A green and facile method was developed by synthesizing a cuprous oxide-carbon dots/Nafion (Cu2O-CDs/NF) composite film for highly sensitive and reliable determination of dopamine (DA). The Cu2O nanoparticles could improve the conductivity of the electrode, while the CDs with carboxyl groups and the NF with sulfo groups could attract cations via the ion-exchange model and exclude anions by the electrostatic action. The proposed biosensor exhibited a low detection limit of 1.1 nM with a wide linear range of 0.05-45.0 mu M and acquired excellent sensitivity and selectivity for DA. Furthermore, the Cu2O-CDs/NF/GCE also was applied to determine DA in human serum with satisfactory results and showed good activity for more than two months.

• 出版日期2015
• 单位厦门大学; 闽南师范大学; 漳州职业技术学院