A Highly Efficient and Stereoselective Cycloaddition of Nitrones to N-Vinylpyrroles

Molchanov Alexander P<sup>*</sup>; Savinkov Ruslan S; Stepakov Alexander V; Starova Galina L; Kostikov Rafael R; Barnakova Victoriya S; Ivanov Andrey V

doi:10.1055/s-0033-1340479

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A Highly Efficient and Stereoselective Cycloaddition of Nitrones to N-Vinylpyrroles

作者：Molchanov Alexander P^*; Savinkov Ruslan S; Stepakov Alexander V; Starova Galina L; Kostikov Rafael R; Barnakova Victoriya S; Ivanov Andrey V

来源：Synthesis (Germany), 2014, 46(6): 771-780.

DOI：10.1055/s-0033-1340479

摘要

1,3-Dipolar cycloadditions of a number of C-aryl, C-carbamoyl-, and C,C-bis(methoxycarbonyl)nitrones and substituted N-vinylpyrroles proceed with high efficiency and regioselectivity with the formation of only one isomeric substituted 5-(1H-pyrrol-1-yl)isoxazolidine cycloadduct.