A red-emitting ratiometric fluorescent probe based on a benzophosphole P-oxide scaffold for the detection of intracellular sodium ions

作者：Taki Masayasu^*; Ogasawara Hiroaki; Osaki Hiroshi; Fukazawa Aiko; Sato Yoshikatsu; Ogasawara Kimi; Higashiyama Tetsuya; Yamaguchi Shigehiro

来源：Chemical communications, 2015, 51(59): 11880-11883.

DOI：10.1039/c5cc03547c

We disclose the development of a ratiometric fluorescent probe based on a benzophosphole P-oxide and its application for the detection of intracellular Na+ ions. Excitation by visible light induced red emission from this probe in water, which was subjected to a hypsochromic shift upon complexation with Na+. Based on this change, a ratiometric analysis enabled us to visualise changes in the Na+ concentration in living mammalian cells.

• 出版日期2015