Axillary hyperhidrosis-efficacy and tolerability of an aluminium chloride antiperspirant - Prospective evaluation on 20 patients with idiopathic axillary hyperhidrosis

作者：Streker M; Reuther T; Verst S; Kerscher M^*

来源：Hautarzt, 2010, 61(2): 139-144.

DOI：10.1007/s00105-009-1841-y

• Axillary hyperhidrosis
• Antiperspirant
• Aluminum chloride solution
• Skin surface pH
• Sweat secretion

The purpose of this study was to evaluate the efficacy and tolerability of aluminium chloride gel for treatment of axillary hyperhidrosis.
A total of 20 patients aged 22-38 (mean age: 26.9 /- 4.3) with idiopathic axillary hyperhidrosis were included and treated with an antiperspirant (Sweat-offA (R), Sweat-offA (R) GmbH, Hugelsheim). Study duration was 42 days. Treatment efficacy was evaluated clinically, as well as by starch-iodine test, gravimetric analysis and evaluation of the skin surface pH.
After treatment there was a significant clinical improvement accompanied by significant qualitative and quantitative reduction of sweat as well as a significant reduction of skin surface pH. Except for slight skin irritation in 6 patients, there were no other side effects. Patient satisfaction improved markedly during the study.
Treatment of axillary hyperhidrosis with aluminium chloride is an effective, safe and inexpensive treatment modality.

• 出版日期2010-2